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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
12.5 DPC

9 matching records from 9 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Foxe3  forkhead box E3   (Synonyms: FREAC8, rct)
Results  Reference
1J:59880 Blixt A, Mahlapuu M, Aitola M, Pelto-Huikko M, Enerback S, Carlsson P, A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle. Genes Dev. 2000 Jan 15;14(2):245-54
1*J:63706 Brownell I, Dirksen M, Jamrich M, Forkhead Foxe3 maps to the dysgenetic lens locus and is critical in lens development and differentiation. Genesis. 2000 Jun;27(2):81-93
1J:77351 Goudreau G, Petrou P, Reneker LW, Graw J, Loster J, Gruss P, Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8719-24
1J:181400 Kuracha MR, Burgess D, Siefker E, Cooper JT, Licht JD, Robinson ML, Govindarajan V, Spry1 and Spry2 are necessary for lens vesicle separation and corneal differentiation. Invest Ophthalmol Vis Sci. 2011 Aug;52(9):6887-97
1J:310318 Li H, Tao C, Cai Z, Hertzler-Schaefer K, Collins TN, Wang F, Feng GS, Gotoh N, Zhang X, Frs2alpha and Shp2 signal independently of Gab to mediate FGF signaling in lens development. J Cell Sci. 2014 Feb 1;127(Pt 3):571-82
1J:116102 Liu W, Lagutin OV, Mende M, Streit A, Oliver G, Six3 activation of Pax6 expression is essential for mammalian lens induction and specification. EMBO J. 2006 Nov 15;25(22):5383-95
1J:177496 Wada K, Maeda YY, Watanabe K, Oshio T, Ueda T, Takahashi G, Yokohama M, Saito J, Seki Y, Takahama S, Ishii R, Shitara H, Taya C, Yonekawa H, Kikkawa Y, A deletion in a cis element of Foxe3 causes cataracts and microphthalmia in rct mice. Mamm Genome. 2011 Dec;22(11-12):693-702
1*J:136711 Zhao H, Yang T, Madakashira BP, Thiels CA, Bechtle CA, Garcia CM, Zhang H, Yu K, Ornitz DM, Beebe DC, Robinson ML, Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88
1J:184697 Zhao J, Kawai K, Wang H, Wu D, Wang M, Yue Z, Zhang J, Liu YH, Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly. Am J Pathol. 2012 Jun;180(6):2230-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory